Fig. 1

The codon bias profile in P. pastoris genome. a Correlation between ω and tAI values in P. pastoris and S. cerevisiae. b Rare codon frequency at the 5′ end of all protein coding genes in P. pastoris (continuous line) and S. cerevisiae (dashed line). c Rare codon frequency at the 5′ end of genes coding for secreted proteins (dashed line) and all protein coding genes (continuous line) in P. pastoris