Nitric oxide donor sodium nitroprusside-induced transcriptional changes and hypocrellin biosynthesis of Shiraia sp. S9

Table 1 Effects of SNP on the individual hypocrellin production in submerged cultures of Shiraia sp. S9

PQ production (mg/L)	EC	EB	HC	EA	HA
Intracellular PQs in mycelia
Control	0.54 ± 0.05	1.03 ± 0.13	5.68 ± 1.90	1.93 ± 0.04	47.05 ± 3.30
SNP	0.50 ± 0.03	1.29 ± 0.23	7.38 ± 0.29	11.34 ± 0.78**	57.54 ± 3.50*
Extracellular PQs in cultural broth
Control	ND	ND	ND	0.13 ± 0.04	2.25 ± 0.20
SNP	ND	ND	ND	0.14 ± 0.02	4.22 ± 0.40**

The SNP at 0.10 mM was added into the mycelium cultures on day 3 and the culture was maintained in 150-mL flask containing 50 mL of the liquid medium at 150 rpm and 28 °C for 8 days. Values are mean ± SD from three independent experiments (*p < 0.05 and **p < 0.01 vs. control). ND indicates no detection

ISSN: 1475-2859