Fig. 8From: Development of the thermophilic fungus Myceliophthora thermophila into glucoamylase hyperproduction system via the metabolic engineering using improved AsCas12a variantsComparative transcriptomics analysis of the MtGM12 mutant and MtWT strain grown in starch medium for 24 and 48Â h. (A) Gene Ontology analysis of the up-regulated genes and down-regulated genes differentially expressed between the MtGM12 and MtWT strains on starch medium. (B) Heatmap analysis of expression profiles for the CAZy genes with statistically significant differences in transcript levels between the MtGM12 vs. MtWT under starch condition. Log-transformed expression values are color-codedBack to article page