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Table 1 The IC50 values (μM) of the purified camptothecin from different fungal sources against various tumor cell lines

From: Production, bioprocessing and antiproliferative activity of camptothecin from Aspergillus terreus, endophyte of Cinnamomum camphora: restoring their biosynthesis by indigenous microbiome of C. camphora

Fungal isolate

Host plant

HepG-2

MCF-7

HCT-116

References

Aspergillus terreus OQ642314.1

Cinnamomum camphora

0.8

0.27

This study

Aspergillus terreus ON908494.1

Cestrum parqui

0.96

1.4

[14]

Penicillium chrysogenum

OL597937.1

Cliona sp.

0.33

0.35

[29]

Aspergillus flavus

MT951414.1

Astragalus fruticosus

0.9

1.2

1.35

[13]

Aspergillus terreus

MW040820

Ficus elastica

0.73

0.18

0.43

[15]