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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Robotic workflows for automated long-term adaptive laboratory evolution: improving ethanol utilization by Corynebacterium glutamicum

Fig. 1

Overview of the robotic workflow for automated long-term rbALE experiments. (A) MPP technology which integrates the microbioreactor BioLector into a liquid handling system. On the right, a typical microtiter plate for cultivation in the micro-bioreactor is shown. The plate is divided into six groups (rows) of eight wells each. The repetitive batches scheme is shown with blue arrows. (B) Flow chart of the long-term rbALE process with well reuse. The process starts with the backscatter (BS) measurement cycle. The measurement data is evaluated after each cycle and when the BS threshold is reached, the inoculation of the next batch and the execution of the washing procedure is triggered

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