Fig. 4From: Impact of cell wall polysaccharide modifications on the performance of Pichia pastoris: novel mutants with enhanced fitness and functionality for bioproduction applicationsBiosynthesis level of SAM in P. pastoris GS115, H001 and H002 under PAOX and PGAP respectively. (a) Schematic representation of SAM biosynthesis, (b) The maximum SAM level. (c) Changes of SAM level by H001/pGAPZ A-sam2 during cultivation. Mean ± SEM are shown (n = 6). Error bars indicate standard deviation. ** represented p < 0.01, *** represented p < 0.001 and **** represented p < 0.0001Back to article page