Fig. 5

Scheme summarizing the main differences between the growths of R. toruloides NRRL Y-6987 in SW₁₅ and in Gly₁₅. Genes upregulated in SW₁₅ (Gly₁₅ as control) are annotated in teal while genes downregulated in SW₁₅ (Gly₁₅ as control) are annotated in crimson. The function or enzyme names are shown in yellow, followed by its rank in terms of contribution to PC1, shown in grey. A dashed arrow represents a potential relation, while solid lines signify a high level of confidence. ACAD acyl-CoA dehydrogenase, ACC acetyl-CoA carboxylase, ACL ATP citrate lyase, ADH alcohol dehydrogenase, Ac-P acetyl-phosphate, dH dehydrogenase, DHAP dihydroxyacetone, ER endoplasmic reticulum, E4P erythrose-4-phosphate, FAS fatty acid synthase, F6P fructose-6-phosphate, GA3P glyceraldehyde-3-phosphate, ICDH isocitrate dehydrogenase, MFS major facilitator superfamily, MS malate synthase, P phosphate, PPP pentose phosphate pathway, PP2A protein phosphatase 2A, RCK radiation sensitivity complementing kinase, RDS regulator of drug sensitivity, X5P xylulose-5-phosphate