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Fig. 1 | Microbial Cell Factories

Fig. 1

From: The strain-dependent cytostatic activity of Lactococcus lactis on CRC cell lines is mediated through the release of arginine deiminase

Fig. 1

Both CFS and > 50 kDa fraction from L. lactis Lc4 strain demonstrate a protein-dependent reduction in cell proliferation. a, c) Confluence of HT-29 (left) and HCT116 (right) in time after treatment with 33% (v/v) CFS (a) or F > 50 kDa (c). GM17 or GM17 > 50 kDa was used as additional control. Graphs represent one biological repetition, performed in 3 technical replicates, error bars represent SD. b, d) Cell growth rate constant after treatment with CFS (b) or F > 50 kDa (d) (n = 3 independent experiments). Data are presented as mean with min to max range. e) Effect of protein digestion on the cytostatic activity of F > 50 kDa fraction. Results represent mean +/- SD for n = 2 independent experiments (*p < 0.05, **p < 0.01, by one-sided t-test)

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Microbial Cell Factories

ISSN: 1475-2859

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