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Fig. 4 | Microbial Cell Factories

Fig. 4

From: LysSYL: a broad-spectrum phage endolysin targeting Staphylococcus species and eradicating S. aureus biofilms

Fig. 4

LysSYL rapidly killed S. aureus cells. A Fluorescent imaging of live/dead bacterial staining. S. aureus USA300 cells were treated with 4×MIC of LysSYL at 37 °C for 1 h. Green fluorescence showed living bacteria and red fluorescence indicated dead bacteria only. PBS treatment served as negative control. B SEM observation of S. aureus USA300 cells after treatment with 4×MIC of LysSYL for 1 h. PBS treatment served as control. The holes formed after LysSYL treatment were indicated by yellow arrows, and the bacterial effluents were showed by white arrows. White bars represent 1 μm. C TEM observation of S. aureus USA300 cells treated with 4×MIC of LysSYL. PBS treatment served as control. Low electron density regions (green arrows) increased and many cellular debris or bacterial ghost cells (red arrows) exhibited. Bars represent 500 nm.

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Microbial Cell Factories

ISSN: 1475-2859

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