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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Engineering Streptomyces sp. CPCC 204095 for the targeted high-level production of isatropolone A by elucidating its pathway-specific regulatory mechanism

Fig. 2

The impact of multiple transcription factors in the isatropolone biosynthetic gene cluster on the production of isatropolones. High-performance liquid chromatography (HPLC) analysis was used to monitor the production of isatropolone A (ISA A) and isatropolone C (ISA C) in the wild type strain (CPCC 204095), the empty vector control strain (CPCC 204095/pSET152), the overexpression strains (CPCC 204095/pL-isaA, CPCC 204095/pL-isaB, CPCC 204095/pL-isaF, CPCC 204095/pL-isaJ), gene knockout strains (AKO, BKO, FKO, and JKO), and genetic complementary strains (FKO/pL-isaF, JKO/pL-isaJ).

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Microbial Cell Factories

ISSN: 1475-2859

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