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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Combinatorial metabolic engineering of Bacillus subtilis enables the efficient biosynthesis of isoquercitrin from quercetin

Fig. 3

Influence of the proposed quercetin degradation pathway genes disruption on isoquercitrin accumulation. (A) Changes of residual quercetin titer by deleting proposed quercetin degradation pathway genes. yxaG, encoding quercetin 2,3-dioxygenase; ydfO, encoding ring-cleaving dioxygenase MhqO; mhqA, encoding ring-cleaving dioxygenase MhqA; yodE, encoding ring-cleaving dioxygenase MhqE; yhjG, encoding aromatic compound monooxygenase; yetG, encoding monooxygenase; yetO, encoding bifunctional P-450/NADPH-P450 reductase; catE, encoding catechol-2,3-dioxygenase; moxC, encoding monooxygenase; ycnE, encoding monooxygenase; yoaI, encoding 4-hydroxyphenylacetate 3-monooxygenase; (B) Changes of isoquercitrin titer by deleting proposed quercetin degradation pathway genes in UGT78D2 overexpressing strains

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Microbial Cell Factories

ISSN: 1475-2859

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