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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Efficient production of 1,2,4-butanetriol from corn cob hydrolysate by metabolically engineered Escherichia coli

Fig. 1

Engineering strategies for 1,2,4-BT production from CCH by recombinant E. coli. Red crosses meant that these genes were deleted. Blue typefaces meant that these genes (xylB, xylC and xylD from Caulobacter crescentus and kdcA from Lactococcus lactis) were overexpressed. xylB, xylose dehydrogenase coding gene. xylC, xylonolactonase coding gene. xylD, xylonate dehydratase coding gene. kdcA, α-ketoacid decarboxylase coding gene. xylA, xylose isomerase coding gene. yjhG/yagF, xylonate dehydratase coding gene. yjhH/yagE, 2-keto-3-deoxy-xylonate aldolase coding gene. yqhD, NADPH-dependent alcohol dehydrogenase coding gene. ptsG, glucose-specific transporter EIICBGlc coding gene. glK, glucose kinase coding gene. pgi, glucose-6-phosphate isomerase coding gene. zwf, glucose-6-phosphate dehydrogenase coding gene. pfk, 6-phosphofructokinase coding gene. gnd, 6-phosphogluconate dehydrogenase coding gene. EMP, Embden-Meyerhof-Parnas pathway. HMP, Hexose Monophosphate pathway. xynR, regulator of xylonate catabolism coding gene. XylE, xylose transporter. AraFGH, arabinose ABC transporter. XylFGH, xylose ABC transporter. GalP, galactose H+ symporter. PTS, phosphotransferase system

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Microbial Cell Factories

ISSN: 1475-2859

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