Table 2 Comparison of 1,2,4-butanetriol production by different microorganisms
Strain | Fermentation method | Substrate | Concentration (g/L) | Yield (mol/mol) | Productivity (g/[L·h]) | Reference |
|---|---|---|---|---|---|---|
E. coli BL21(DE3)/pWN6.222A | Batch fermentation in 1-L bioreactor | l-Arabinonic acid | 2.4 | 0.35 | NFa | [17] |
E. coli DH5α/pWN6.186A | Batch fermentation in 1-L bioreactor | d-Xylonic acid | 1.6 | 0.25 | NFa | [17] |
E. coli EWBT304 | Batch fermentation in 300 mL shake flasks | Xylose | 0.88 | 0.13 | 0.02 | [18] |
E. coli as3KXW004 | Batch fermentation in 50 mL LB medium | Xylose | 10.03 | 0.47 | 0.21 | [19] |
Saccharomyces cerevisiae BDδK6035 | Fed-batch fermentation in 1.0-L bioreactors | Glucose and xylose | 6.60 | 0.57 | 0.05 | [20] |
S. cerevisiae BDδD-2tkdcA-ΔBOL2-tTYW1 | Batch fermentation in 200 mL-baffled erlenmeyer flask | Glucose and xylose | 1.70 | 0.25 | 0.02 | [21] |
E. coli R1 | Fed-batch fermentation in 50 mL fermentation medium | Glucose and xylose | 14.4 | NFa | NFa | [28] |
E. coli BL21-14 | Batch fermentation in 500-mL shake flasks | Xylose | 5.1 | 0.18 | 0.07 | [32] |
E. coli MJ134k-1 | Batch fermentation in 50 mL medium of 250 mL shake flasks | Glucose and xylose | 3.96 | 0.24 | 0.11 | [33] |
E. coli BL21ΔxylAB/pE-mdlCxylBC&pA-adhPyjhG | Fed-batch fermentation in 5 L-scale bioreactor | Glycerol and xylose | 3.92 | 0.28 | 0.07 | [34] |
E. coli (pEtac-mdlC-tac-xylB) | Batch fermentation in 20 mL LB medium | Xylose | 0.90 | 0.04 | 0.02 | [35] |
E. coli W031 | Batch fermentation in 5-L bioreactor | Glucose and xylose | 3.9 | 0.3 | NFa | [36] |
E. coli BT-10 | Fed-batch fermentation in 7.5-L bioreactor | Glucose and xylose | 36.63 | 0.66 | 1.14 | This study |
E. coli BT-10 | Fed-batch fermentation in 7.5-L bioreactor | Corn cob hydrolysate | 43.40 | 0.90 | 1.09 | This study |